Known Result :
Let $I$ be a proper ideal in the integral domain $R$ and let $p(x)$ be a non constant polynomial in $R[x]$. If the image of $p(x)$ in $(R/I)[x]$ is irreducible then $p(x)$ is irreducible in $R[x]$.
This is actually slightly general than Eisenstein. If you want some reference I would suggest you to look at "Dummit Foote -Abstract Algebra -Polynomial Rings -Irreducibility".
Now, $X^6-15X^4-6X^3+75X^2-90X-116$ after going modulo $2$ gives you $x^6-x^4+x^2$ which is seen to be reducible in the first sight.
Now, $X^6-15X^4-6X^3+75X^2-90X-116$ after going modulo $3$ gives you (??). This can be seen to be reducible (??) (Trust me i will not make you do laborious work )
Now, $X^6-15X^4-6X^3+75X^2-90X-116$ after going modulo $5$ gives you (??). This can be seen to be reducible (??) (Trust me i will not make you do laborious work )
Now, $X^6-15X^4-6X^3+75X^2-90X-116$ after going modulo $7$ gives you (??). As claimed by Mr.Martin, This is Irreducible.
I prefer going modulo some prime because this would give a finite field $\mathbb{Z}_p$ and it would not be so difficult to find irreducible polynomials of given degree.
Once you know all irreducible polynomials of degree $2$ and $3$ in $\mathbb{Z}_7$ then you are done...
Just make sure no irreducible polynomial you got of degree $2$ and $3$ divides your $p(x)$ (on $\mathbb{Z}_7$).
Thus, you found some prime $p$ in this case it is $7$ such that $p(x)$ is irreducible in $\mathbb{Z}_7$ and by above stated result $p(x)$ is irreducible in $\mathbb{Z}[x]$ and so is in $\mathbb{Q}[x]$ (why ??)
P.S : This is not any better than other ways but I felt it would be a good way to conclude irreducibility.. choosing a prime $p$ in this case is as difficult as choosing prime $p$ in eisenstein :D so this is not the worst way :).