What does test the model for significance mean?

Say that I have a model $\hat Y_i=\hat \beta_0+\hat \beta_1X_{i1}+\hat \beta_2X_{i2}+u_i$, where $X_{i1}$ is a binary variable that takes the value 1 if female and 0 if male, and $\hat Y$ is the estimated weight of the baby. The question asks to test whether the estimated model is statistically different for male and female babies. I am confused which test the question is asking for and which variable is to be tested.