Can you define multiplication with out addition? For natural numbers (i.e. $0,1,2,\dots$), sure. I'm not sure why you would want to do this, but it could be done as follows:
Let $0=\phi=\{\}$ (the empty set), $1 = \{0\}$, $2 = 1 \cup \{1\} = \{0,1\}$, $3 = 2 \cup \{2\} = \{0,1,2\}$, $\dots$
Define $m \times n = \{ (i,j) \;|\; i \in m \mbox{ and } j \in n\}$ (the Cartesian product of $m$ and $n$ -- all ordered pairs). Then set $m \times n$ can be put into 1-1 correspondence with some natural number (set). Call this number $m \cdot n$. Voila! Multiplication.
Ok. Now for a reality check. When defining the natural numbers themselves I've used succession (i.e. plus one): $n+1 = n \cup \{n\}$ (so there's addition hiding in the very definition of a natural number).
Next, if I were to actually prove that $m \times n$ is in 1-1 correspondence with some natural number, I would almost certainly end up developing addition to do so.
So can you avoid addition? Yes and no. But necessarily in an unnatural way.
Exponentiation is repeated multiplication: $m^n = m^{n-1}m$. Multiplication is repeated addition: $mn = m(n-1)+m$. Addition is repeated succession: $n+m = n+(m-1)+1$. It's just a natural hierarchy of operations.
All arithmetic for bigger number systems flows from this.