It is not hard to check that $V$ is a vector space.
Since $A$ is a $p \times q$ matrix of rank $\alpha$, an invertible $p \times p$ matrix $F_1$ and an invertible $q \times q$ matrix $F_2$ exist such that
$$
A = F_1 A_0 F_2,
$$
in which
$$
A_0 = \begin{bmatrix}
I_{\alpha} & 0_{\alpha \times (q - \alpha)} \\
0_{(p - \alpha) \times \alpha} & 0_{(p - \alpha) \times (q - \alpha)} \\
\end{bmatrix}.
$$
Since $B$ is an $r \times s$ matrix of rank $\beta$, an invertible $r \times r$ matrix $G_1$ and an invertible $s \times s$ matrix $G_2$ exist such that
$$
B = G_1 B_0 G_2,
$$
in which
$$
B_0 = \begin{bmatrix}
I_{\beta} & 0_{\beta \times (s - \beta)} \\
0_{(r - \beta) \times \beta} & 0_{(r - \beta) \times (s - \beta)} \\
\end{bmatrix}.
$$
Hence $ACB = 0$ becomes
$$
F_1 A_0 (F_2 C G_1) B_0 G_2 = 0_{p \times s},
$$
which means
$$
A_0 (F_2 C G_1) B_0 = 0_{p \times s}.
$$
Denote the $q \times r$ matrix $F_2 C G_1$ by $X$.
It is not hard to find that $A_0 X B_0 = 0$ if and only if
$$
[X]_{i,j} =0 \qquad \text{for $i \leq \alpha$ and $j \leq \beta$},
$$
in which $[X]_{i,j}$ is the $(i,j)$-entry of $X$.
Let $E_{u,v}$ be the $q \times r$ matrix with the property that
$$
[E_{u,v}]_{i,j}
= \begin{cases}
1, & \text{$u = i$ and $v = j$}; \\
0, & \text{else}.
\end{cases}
$$
Let $J$ be the set
$$
\{ F_2^{-1} E_{u,v} G_1^{-1} \mid \text{$u > \alpha$ or $v > \beta$} \}.
$$
(1) Every solution to $ACB = 0$ is some linear combination of the members of $J$. If $A C_0 B = 0$, then $A_0 (F_2 C_0 G_1) B_0 = 0$, which means
$$
[F_2 C_0 G_1]_{i,j} =0 \qquad \text{for $i \leq \alpha$ and $j \leq \beta$}.
$$
Hence
$$
\begin{aligned}
F_2 C_0 G_1
= {} &\sum_{\substack{
1 \leq i \leq q \\
1 \leq j \leq r \\
}} {[F_2 C_0 G_1]_{i,j} E_{i,j}}
\\
= {} &
\sum_{\substack{
1 \leq i \leq q \\
1 \leq j \leq r \\
i \leq \alpha \,\text{and}\, j \leq \beta
}} {[F_2 C_0 G_1]_{i,j} E_{i,j}}
+
\sum_{\substack{
1 \leq i \leq q \\
1 \leq j \leq r \\
i > \alpha \,\text{or}\, j > \beta
}} {[F_2 C_0 G_1]_{i,j} E_{i,j}}
\\
= {} &
\sum_{\substack{
1 \leq i \leq q \\
1 \leq j \leq r \\
i > \alpha \,\text{or}\, j > \beta
}} {[F_2 C_0 G_1]_{i,j} E_{i,j}},
\end{aligned}
$$
which means
$$
C_0 = F_2^{-1} (F_2 C_0 G_1) G_1^{-1}
=
\sum_{\substack{
1 \leq i \leq q \\
1 \leq j \leq r \\
i > \alpha \,\text{or}\, j > \beta
}} {[F_2 C_0 G_1]_{i,j} (F_2^{-1} E_{i,j} G_1^{-1})}.
$$
(2) The members of $J$ are linearly independent.
Suppose that
$$
\sum_{\substack{
1 \leq i \leq q \\
1 \leq j \leq r \\
i > \alpha \,\text{or}\, j > \beta
}} {k_{i,j} (F_2^{-1} E_{i,j} G_1^{-1})} = 0.
$$
Hence
$$
F_2 \left( \sum_{\substack{
1 \leq i \leq q \\
1 \leq j \leq r \\
i > \alpha \,\text{or}\, j > \beta
}} {k_{i,j} (F_2^{-1} E_{i,j} G_1^{-1})} \right) G_1 = 0.
$$
Hence
$$
\sum_{\substack{
1 \leq i \leq q \\
1 \leq j \leq r \\
i > \alpha \,\text{or}\, j > \beta
}} {k_{i,j} E_{i,j}} = 0.
$$
Hence $k_{i,j} = 0$.
We have shown that the members of $J$ form a basis of $V$.
$J$ has $rq - \alpha \beta$ members, so the dimension of $V$ is the number of the members of $J$, $rq - \alpha \beta$.