We know that $e^{\pi \sqrt{163}}$ is very close to an integer(see wikipedia), and there is no closer to an integer than $163$ when $n$ is less than $1$ million.
Can we prove such a strengthened proposition:
the decimal part of $l_n = e^{\pi \sqrt{n}}, n \in \mathbb{Z}$ is dense on $(0, 1)$.
In this way, $l_n$ can approach $\alpha\in (0, 1)$, so we can know that $l_{163}$ is not the one closest to integers.