Good answers, here. FWIW, here is a possible proof using Fitch-style natural deduction system and the rules present in the book "Logic: The Laws of Truth".
$
\def\fitch#1#2{\quad\begin{array}{|l}#1\\\hline#2\end{array}}
\def\Ae#1{\qquad\mathbf{\forall E} \: #1 \\}
\def\Ai#1{\qquad\mathbf{\forall I} \: #1 \\}
\def\Ee#1{\qquad\mathbf{\exists E} \: #1 \\}
\def\Ei#1{\qquad\mathbf{\exists I} \: #1 \\}
\def\R#1{\qquad #1\,(\mathbf{RI}) \\}
\def\ci#1{\qquad #1\,(\mathbf{\land I})\\}
\def\ce#1{\qquad\mathbf{\land E} \: #1 \\}
\def\oi#1{\qquad #1\,(\mathbf{\lor I}) \\}
\def\oe#1{\qquad\mathbf{\lor E} \: #1 \\}
\def\ii#1{\qquad\mathbf{\to I} \: #1 \\}
\def\ie#1{\qquad\mathbf{\to E} \: #1 \\}
\def\be#1{\qquad\mathbf{\leftrightarrow E} \: #1 \\}
\def\bi#1{\qquad #1\,(\mathbf{\leftrightarrow I})\\}
\def\qi#1{\qquad\mathbf{=I}\\}
\def\qe#1{\qquad\mathbf{=E} \: #1 \\}
\def\ne#1{\qquad #1\,(\mathbf{\lnot E})\\}
\def\ni#1{\qquad #1\,(\mathbf{\lnot I})\\}
\def\IP#1{\qquad\mathbf{IP} \: #1 \\}
\def\x#1{\qquad\mathbf{X} \: #1 \\}
\def\DNE#1{\qquad\mathbf{DNE} \: #1 \\}
$
$
\fitch{}{
\fitch{1.\,\lnot(P \land Q)}{
\fitch{2.\,\lnot(\lnot P \lor \lnot Q)}{
\fitch{3.\,P}{
\fitch{4.\,Q}{
5.\,P \land Q \ci{3,4}
6.\,\lnot(P \land Q) \R{1}
}\\
7.\,\lnot Q \ni{4-6}
8.\,\lnot P \lor \lnot Q \oi{7}
9.\,\lnot(\lnot P \lor \lnot Q) \R{2}
}\\
10.\,\lnot P \ni{3-9}
11.\,\lnot P \lor \lnot Q \oi{10}
12.\,\lnot(\lnot P \lor \lnot Q) \R{2}
}\\
13.\,\lnot P \lor \lnot Q \ne{2-12}
}\\
14.\,\lnot(P \land Q) \to (\lnot P \lor \lnot Q) \ii{1-13}
}
$