Let $ X $ be an $ n+1 $ dimensional manifold. Suppose that $ M_1$ and $ M_2 $ are compact manifolds with boundary such that $ M_1 $ and $ M_2 $ both have interior homeomorphic to $ X $. Let $ Y_1 $ be the boundary of $ M_1 $ and $ Y_2 $ the boundary of $ M_2 $. Is it the case that $ Y_1 $ must be homeomorphic to $ Y_2 $?
As a sort of converse, suppose that $ M_1,M_2 $ are compact manifolds with boundary and moreover their boundaries are homeomorphic. Consider the interior $ X_1 $ of $ M_1 $ and the interior $ X_2 $ of $ M_2 $. Do $ X_1 $ and $ X_2 $ just differ by taking connected sum with closed $ n+1 $ manifolds? By that I mean something like: Is it the case that there exist closed $ n+1 $ manifolds $ Z_1 $ and $ Z_2 $ such that $$ X_1 \# Z_1 \cong X_2 \# Z_2 $$
For the first question, my idea for existence is that you can take any tubular neighborhood of the $ n+1 $ manifold $ X $, then embed that into some $ \mathbb{R}^k $. For any such embedding the boundary of the image of $ X $ under the embedding should give you the same $ n $ manifold $ Y $ (also $ X $ should be noncompact otherwise $ Y $ is just the empty set viewed as an $ n $ manifold).