Uncountable homogeneous linear orders Let $(S,\leq)$ be a countable linear order with the following property (H):
for all positive integers $n$, and all increasing sequences $s_1 < s_2 < \ldots < s_n$ and $t_1 < t_2 < \ldots < t_n$, there is an order automorphism $\alpha$ of $S$ such that $\alpha(s_i) = t_i$ for all $i
= 1, 2, \ldots, n$.
Then by a result of Cantor, $(S,\leq)$ is order isomorphic to $(\mathbb{Q},\leq)$. 
Now suppose that $S$ is not countable, but also having property (H). It seems to me that the order automorphism group of $(S,\leq)$ should share many properties with the order automorphism group of $(\mathbb{Q},\leq)$. 
What are some of the important properties that they do not share ? What are the (main) differences ?
 A: One difference is the number of orbits of increasing length-$\omega$ sequences. This isn't really a difference in the automorphism groups per se, but rather their actions, but I think it's interesting enough to note.

In $Q=(\mathbb{Q},<)$ there are exactly three kinds of increasing sequence (up to automorphism, in the sense that any two sequences of the same type can be swapped by an automorphism of $Q$). Namely, an increasing sequence $(a_i)_{i\in\omega}$ of rationals has exactly one of the following three properties, and if $(a_i)_{i\in\omega},(b_i)_{i\in\omega}$ have the same property then there is an automorphism $\alpha$ of $Q$ such that $\alpha(a_i)=b_i$ for all $i\in\omega$:


*

*Unbounded: the set $\{a_i:i\in\omega\}$ has no upper bound.

*Bounded but no least upper bound: the sequence is bounded but whenever $b\in Q$ is such that $b>a_i$ for all $i$ there is some $c\in Q$ such that $c>a_i$ for all $i$ and $c<b$.

*Has a least upper bound: there is some $b\in Q$ such that $b>a_i$ for all $i$ and for all $c<b$ there is some $i$ such that $c<a_i$.
For example, taking $a_i=i$ yields a sequence of the first type, taking $a_i=\pi-{1\over i+1}$ yields a sequence of the second type (the "$+1$" addresses the case $i=0$), and taking $a_i=1-{1\over i+1}$ yields a sequence of the third type.
By contrast, this can fail for uncountable orders with property (H). For example, $R=(\mathbb{R},<)$ has property $(H)$ but only two types of increasing $\omega$-sequences (every bounded sequence has a least upper bound).


*

*As an aside, this is fundamentally impossible in the countable context: Vaught's never-two theorem says that no complete theory in a countable language can have exactly two countable models up to isomorphism. Gauging the number of models of a theory of a given cardinality is a major theme in model theory - for example, if $T$ is a complete theory in a countable language then the number of countably infinite models of $T$ is either finite, $\aleph_0$, $\aleph_1$, or $2^{\aleph_0}$. Every finite value other than $2$ is possible, as are $\aleph_0$ and $2^{\aleph_0}$; it is unknown whether (in case $\aleph_1\not=2^{\aleph_0}$) the case $\aleph_1$ is possible. It's also worth noting that there's a rephrasing of Vaught's conjecture that doesn't trivialize under the continuum hypothesis (see here).

A: We usually think of automorphism groups not just as groups, but as topological groups, under the topology of pointwise convergence. Then the automorphism group of any countable structure is a Polish group: it is separable and completely metrizable. On the other hand, if $M$ is an uncountable structure in which some point has an uncountable orbit (for example, if $M$ is an uncountable homogeneous linear order in your sense), then $\text{Aut}(M)$ has an uncountable family of disjoint open sets, so it is not separable. 
