With a few data points can a generate a close equation to meet them? I have
1x = -40, 2x = -41 , 3x = -54

and getting a few more. Can I generate a equation for a graph that gets close to this?
I was trying to get Wolfram Alpha to do this. 
EDIT:
Sorry for lack of clarity
I am hand measuring signal to distance in meters
I have
at 1 meter: -40 (signal strength)
at 2 meter: -41
at 3 meter: -54

And I could keep measuring
is it possible to come up with some kind of math to estimate signal strength for  any distance?
Im thinking smooth line on a scatter plot
 A: The process of fitting a smooth curve (or surface) to a set of data points is called non-linear regression and is part of statistics.  For an overview see:
http://en.wikipedia.org/wiki/Nonlinear_regression .
There are many curves that will fit your data.  Getting more points is a good idea.  See also "curve fitting" here: http://en.wikipedia.org/wiki/Curve_fitting
There are some online tools for this.  For example, if you want to fit your data with a polynomial go here http://www.xuru.org/rt/PR.asp 
For other types of curve fitting try:  http://www.xuru.org/rt/TOC.asp 
Of course there is commercial software for this and other statistical modeling tasks as well.
A: You have given three data points:  (1,-40), (2,-41), (3,-54).  Through any $n$ points there will be a polynomial of degree at most $n-1$, so there will be a quadratic that fits them exactly.  Lagrange interpolation is one way to find the polynomial.  Excel has it built in.  However, the interpolation can be very sensitive to errors of measurement, so you might want to fit the best quadratic through more points.  It will not go exactly through the points, but will be much less sensitive to error.  Again, Excel will do the fit to any order you like.  Chapter three in Numerical Recipes (obsolete versions are  free) has a good discussion.
If these are signal strengths measured in dB, you would actually expect that once you get far enough away they should fit a straight line if you take the logarithm of the distance.  The power drops as $r^{-2}$ and taking the logarithm makes that a line.  The three you give do not.
