While other answers have pointed out the problem of defining a random quadratic, I will argue that there are, indeed, rather interesting measures on the quadratics.
Let $ax^2+bx+c=0$ be the equation of a parabola. Il we multiply all the coefficients by some constant, we get e.g.
$$10ax^2+10bx+10c=0,$$
which is another equation of the same curve. Hence, instead of taking for $(a,b,c)$ general real numbers, we can normalize, for instance by adding the constraint $a^2+b^2+c^2 = 1$. Then $(a,b,c)$ lie on a sphere, on which there is a natural probability measure: the uniform measure. The simplest way to simulate this setting is to take for $a$, $b$ and $c$ three independent standard Gaussians; then $(a,b,c)/ \|a^2+b^2+c^2\|$ is uniform on the unit sphere.
Note that (as per Leftaroundabout's comment) this is just one possible normalization, and thus one possible measure on quadratics, called Kac's random polynomial. There are other reasonable measures. However, this one in particular gives rise to some interesting and not too difficult pieces of mathematics.
Anyway, whichever normalization you choose, this highlights a feature of this problem which is not very visible in Michael Seifert's answer: the quadratics having no $x$-intercept are exactly those whose coefficients satisfy $b^2-4ac<0$, which is, in parameter space, the equation of a filled cone (try to plot it on Mathematica and to move the object around). The point of view above interprets "the proportion of quadrics having no $x$-intercept" as "the proportion of directions in parameter space corresponding to quadrics having no $x$-intercept", or equivalently "the proportion of quadratics with $a^2+b^2+c^2 \leq 1$ having no $x$-intercept".
Under this setting, and if I'm not mistaken, a quick computation gives me that the probability of having no $x$-intersect is:
$$1-\frac{1}{2\pi}\int_{\mathbb{R}} \frac{\sqrt{t^4+4t^2+1}}{t^4+t^2+1} \ dt \simeq 0,351.$$
Reference : How many zeroes of a random polynomial are real?, A. Edelman and E. Kostlan, Bulletin of the AMS, Vol. 32, n.1, January 1995. Available on arXiv: https://arxiv.org/pdf/math/9501224.pdf
The formula above is due to Kac (1943). I will let somebody else try to find a closed form, as there are poeple here much better than me at identifying and computing integrals.