In $\mathbb{R}^3$, up to a sign, the volume of a tetrahedron with vertices at $\vec{v}_0 = \vec{0}$, $\vec{v}_1$, $\vec{v}_2$ and $\vec{v}_3$ is given by a scalar triple product:
$$\verb/Volume/ = \frac16 \left| \vec{v}_1 \cdot ( \vec{v}_2 \times \vec{v}_3 ) \right|$$
If one construct a $3 \times 3$ matrix $\Delta$ whose $i^{th}$ column equals to $\vec{v}_i$, above formula becomes
$$\verb/Volume/ = \frac16 | \det\Delta |$$
Let $G(\vec{v}_1,\vec{v}_2,\vec{v}_3) = \Delta^T\Delta$ be the Gram matrix associated with the vectors $\vec{v}_1$, $\vec{v}_2$ and $\vec{v}_3$. For the purpose of this question, it is simply a $3 \times 3$ matrix whose entry at row $i$, column $j$ equals to $\vec{v}_i\cdot\vec{v}_j$. Since these
entries depend only on inner products, the expression continues to work even when the points belong to some higher dimension space.
In terms of the Gram matrix, the 3-volume
of a tetrahedron with vertices $\vec{u}_0$, $\vec{u}_1$, $\vec{u}_2$, $\vec{u}_3 \in \mathbb{R}^n$ for any $n \ge 3$ equals to
$$\verb/Volume/ = \frac16\sqrt{\det G(\vec{v}_1,\vec{v}_2,\vec{v}_3)}
\quad\text{ where }\quad \vec{v}_i = \vec{u}_i - \vec{u}_0$$
For the problem at hand
$$\begin{cases}
\vec{v}_1 = (-2,2,0,0)\\
\vec{v}_2 = (\phantom{+}2,0,1,0)\\
\vec{v}_3 = (-2,4,0,0)
\end{cases}
\implies G(\vec{v}_1,\vec{v}_2,\vec{v}_3) =
\begin{bmatrix}
\vec{v}_1\cdot\vec{v}_1 & \vec{v}_1\cdot\vec{v}_2 & \vec{v}_1\cdot\vec{v}_3\\
\vec{v}_2\cdot\vec{v}_1 & \vec{v}_2\cdot\vec{v}_2 & \vec{v}_2\cdot\vec{v}_3\\
\vec{v}_3\cdot\vec{v}_1 & \vec{v}_3\cdot\vec{v}_2 & \vec{v}_3\cdot\vec{v}_3\\
\end{bmatrix}
=
\begin{bmatrix}
8 & -4 & 12 \\
-4 & 5 & -4 \\
12 & -4 & 20
\end{bmatrix}
$$
This leads to
$$\verb/Volume/ = \frac16 \sqrt{\left|\begin{matrix}
8 & -4 & 12 \\
-4 & 5 & -4 \\
12 & -4 & 20
\end{matrix}\right|}
= \frac16\sqrt{16} = \frac{2}{3}$$
Update
For an alternative formula for the volume, we can apply Cauchy-Binet formula to $\det(\Delta^T\Delta)$ and decompose it as a sum of squares of determinants of
$3 \times 3$ sub-matrices of $\Delta$. More precisely, let $\vec{r}_1, \vec{r}_2, \ldots, \vec{r}_n \in \mathbb{R}^3$ be the row vectors of $\Delta$, we have
$$\det(G) = \det(\Delta^T\Delta) = \sum_{1 \le i < j < k \le n}
| \vec{r}_i \cdot ( \vec{r}_j \times \vec{r}_k )|^2$$
When $n = 4$, the volume of a tetrahedron becomes
$$\verb/Volume/ = \frac16\sqrt{
| \vec{r}_1 \cdot ( \vec{r}_2 \times \vec{r}_3 )|^2
+| \vec{r}_1 \cdot ( \vec{r}_2 \times \vec{r}_4 )|^2
+| \vec{r}_1 \cdot ( \vec{r}_3 \times \vec{r}_4 )|^2
+| \vec{r}_2 \cdot ( \vec{r}_3 \times \vec{r}_4 )|^2}$$
For the problem at hand,
$\begin{cases}
\vec{r}_1 = (-2,2,-2)\\
\vec{r}_2 = (2,0,4)\\
\vec{r}_3 = (0,1,0)\\
\vec{r}_4 = (0,0,0)
\end{cases}$.
Since $\vec{r}_4 = \vec{0}$, only one triple product survives and
$$\verb/Volume/
= \frac16 | \vec{r}_1 \cdot (\vec{r}_2 \times \vec{r}_3)|
= \frac16
\left|\begin{bmatrix}
-2 & 2 & -2\\
2 & 0 & 4\\
0 & 1 & 0
\end{bmatrix}\right|
= \frac{|(-2)4 - (-2)(2)|}{6}
= \frac23
$$
Same answer as before. In general, this illustrate if one component of $u_k$ is the same, then some row vectors $\vec{r}_k = \vec{0}$. Up to a constant, the formula of volume reduce to a scalar triple product again.