FIRST CASE. If you had only one set of values for $I$ and $R$, as you said in your answer to Rasmus, then you'd have a system of linear equations with infinitely many solutions.
For psychological reasons, let's write it this way:
$$
XA = B \ .
$$
Here $A$ is your $R$, $B$ your $I$ and $X$ your $A$. If we transpose we get a simultaneous system of linear equations
$$
A^t X^t = B^t \ .
$$
If $A^t = (a_1 \ a_2 \ a_3)$ and $B^t = (b_1 \ b_2 \ b_3)$, and $(x_i \ y_i \ z_i)$ is the i-th colum $X^t$, we have the linear equations
$$
a_1 x_i + a_2 y_i + a_3 z_i = b_i
$$
for $i = 1, 2, 3$.
Which, assuming $a_1 \neq 0$, you can solve like this:
$$
x_i = \frac{b_i}{a_1} - \frac{a_2}{a_1} y_i - \frac{a_3}{a_1} z_i \ .
$$
Now, give $y_i$ and $z_i$ the values you want and you have a solution for your problem.
EDIT: Maybe I could develop a little bit more my answer, in order to really include your problem, which is one of overdeterminated simultaneous systems of linear equations, as KennyTM says, since you don't have a prefered pair of values $(R,I)$, do you? In order to handle all the $24$ pairs of values $(R,I)$ you have, maybe you should take into account this SECOND CASE.
SECOND CASE. I'm sorry, but I'm changing slightly the notation again. In the end, I'll write the solution with yours.
Let
$$
AX = B
$$
be a (simultaneous) system of linear equations such as yours, with $A$ a $24\times 3$ matrix ($24$ rows, $3$ columns), $X$ a $3\times 3$ matrix and $B$ a $24 \times 3$ matrix.
**Hypothesis: Let's assume that our matrix $A$ (that is, your $R$) has rang $ 3$. **
(If this is not the case, the problem is more involved.)
Let's write the first system this way:
$$
x_1a_1 + y_1a_2 + z_1a_3 = b_1 \ . \qquad [1]
$$
Here, $a_i , i = 1,2,3$ are the columns of $A$, $X_1 = \begin{pmatrix} x_1 & y_1 & z_1 \end{pmatrix}^t$ the first column of $X$ and also $b_1$ is the first column of $B$.
So we see in one go a geometrical interpretation of our system of equations: system [1] has a solution $\begin{pmatrix} x_1 & y_1 & z_1 \end{pmatrix}$ if and only if the vector $b_1$ belongs to the linear span generated by the columns of $A$:
$$
AX_1 = b_1 \quad \text{has a solution} \qquad \Longleftrightarrow \qquad b_1 \in [a_1, a_2, a_3]
$$
What can we do if this is not the case? -To look for the nearest vector in $[a_1, a_2, a_3]$ to $b_1$.
This nearest vector is, of course, the orthogonal projection of $b_1$ onto the subspace $[a_1, a_2, a_3] $.
According to Wikipedia, http://en.wikipedia.org/wiki/Orthogonal_projection , the matrix of this orthogonal projection in the standard basis of $\mathbb{R}^{24}$ is
$$
P_A = A (A^tA)^{-1}A^t \ .
$$
So the best $X = \begin{pmatrix} X_1 & X_2 & X_3\end{pmatrix}$ for you is
$$
X = A (A^tA)^{-1}A^tB
$$
where $B = \begin{pmatrix} b_1 & b_2 & b_3 \end{pmatrix}$. Now, let's go back to your notation: $A = X^t$, $R = A^t$ and $I = B^t$. So
$$
A = \left( R^t (R^{tt}R^t)^{-1}R^{tt}I^t \right)^t = I R^t ((RR^t)^{-1})^t R
$$
where $R$ and $I$ are now the matrices with all of your $R$'s and $I$'s as columns.