This answer is based upon a result stated as example 1.3 in the paper Log-concavity and LC-positivity by Yi Wang and Yeong-Nan Yeh.
In the following we consider natural numbers $0\leq s\leq t,\,0\leq n$ and use the convention $\binom{n}{k}=0$ if $k>n$ or $k<0$. We obtain using $\binom{n}{k}=\binom{n-1}{k}+\binom{n-1}{k-1}$
\begin{align*}
\color{blue}{a_n}&=\sum_{k=s}^t\binom{n}{k}\\
&=\sum_{k=s}^t\binom{n-1}{k}+\sum_{k=s}^t\binom{n-1}{k-1}\\
&=\sum_{k=s}^t\binom{n-1}{k}+\sum_{k=s-1}^{t-1}\binom{n-1}{k}\tag{1}\\
&\color{blue}{=2a_{n-1}+\binom{n-1}{s-1}-\binom{n-1}{t}}\tag{2}
\end{align*}
Comment:
- In (1) we shift the index of the right-hand sum to start with $k=s-1$ and collect in the next line equal terms to $2a_{n-1}$.
In order to show $a_{n-1}a_{n+1}\leq a_n^2$ we calculate
\begin{align*}
\color{blue}{a_n^2}&\color{blue}{-a_{n-1}a_{n+1}}\\
&=a_n\left(2a_{n-1}+\binom{n-1}{s-1}-\binom{n-1}{t}\right)
-a_{n-1}\left(2a_n+\binom{n}{s-1}-\binom{n}{t}\right)\tag{3}\\
&=\left[\binom{n-1}{s-1}a_n-\binom{n}{s-1}a_{n-1}\right]
-\left[\binom{n-1}{t}a_n-\binom{n}{t}a_{n-1}\right]\\
&=\sum_{k=s}^t\left[\binom{n-1}{s-1}\binom{n}{k}-\binom{n}{s-1}\binom{n-1}{k}\right]\\
&\qquad-\sum_{k=s}^t\left[\binom{n-1}{t}\binom{n}{k}-\binom{n}{t}\binom{n-1}{k}\right]\\
&=\sum_{k=s}^t\left[\binom{n-1}{s-1}\binom{n-1}{k-1}-\binom{n-1}{s-2}\binom{n-1}{k}\right]\\
&\qquad-\sum_{k=s}^t\left[\binom{n-1}{t}\binom{n-1}{k-1}-\binom{n-1}{t-1}\binom{n-1}{k}\right]\tag{4}\\
&\color{blue}{=\sum_{k=s}^t\left[\binom{n-1}{s-1}\binom{n-1}{k-1}-\binom{n-1}{s-2}\binom{n-1}{k}\right]}\\
&\qquad\color{blue}{+\sum_{k=s}^t\left[\binom{n-1}{k}\binom{n-1}{t-1}-\binom{n-1}{k-1}\binom{n-1}{t}\right]}\tag{5}
\end{align*}
Comment:
In (3) we replace one factor $a_n$ and $a_{n+1}$ by the identity stated in (2).
In (4) we use again in both sums the binomial identity $\binom{n}{k}=\binom{n-1}{k-1}+\binom{n-1}{k}$ twice and cancel terms.
In (5) we do a simple rearrangement, nothing else.
We now take a closer look at the summands of the first sum in (5)
\begin{align*}
\sum_{k=s}^t\left[\color{blue}{\binom{n-1}{s-1}\binom{n-1}{k-1}-\binom{n-1}{s-2}\binom{n-1}{k}}\right]\tag{6}
\end{align*}
It is well-known that the binomial coefficients $\binom{n}{k}$ are log-concave in $k$ ($n$ fix). Furthermore the following is valid: A sequence $x_k$ is log-concave if and only if
\begin{align*}
x_{i-1}x_{j+1}\leq x_ix_j\qquad\qquad \text{for all }j\geq i\geq 1
\end{align*}
This is also stated in the referred paper in the introduction right at the beginning.
Conclusion: From this we conclude the summands in (6) are all non-negative and therefore the sum is non-negative. The same arguments hold also for the second sum in (5) and so the claim follows.
Note: The following papers might be interesting: