$M_1:=\cup_{n\in\mathbb{N}}(n,n+1)$: Since every $(n,n+1)$ is open, the union is open as well. Hence the interior points of $M_1$ are $M_1$. The closure of $M_1$ is just $\{x\in\mathbb{R}:\ x\geq 0\}$ (if you define the natural numbers with zero), since you can approximate every natural number $n$ by the sequence $(n+\frac{1}{k})_{k\in\mathbb{N}}$, which lies in $M_1$. With the same argument you get the accumulation points as well.
$M_2:=\mathbb{Q}\cap([1,3]\cup[-\pi,0])\cup\{4,5,6\}$: $M_2$ has no interior points, since every $q\in M_2$ is rational. Therefore for every $\varepsilon>0$ you can find an irrational number in the ball $B_\varepsilon(q)$. This means $q$ is not an interior point. The closure can be dealt with as follows. Since $\mathbb{Q}$ is dense in $\mathbb{R}$ you have $\overline{M_2}=[1,3]\cup[-\pi,0]\cup\{4,5,6\}$. The accumulation points are $\mathbb{Q}\cap([1,3]\cup[-\pi,0])$, since again $\mathbb{Q}$ is dense. Therefore for every $\varepsilon>0$ and every $q\in \mathbb{Q}\cap([1,3]\cup[-\pi,0])$ the set $(B_{\varepsilon}(q)\setminus q)\cap M_2$ is not empty. The other points $\{4,5,6\}$ can be dealt by choosing $\varepsilon=\frac{1}{2}$. For this $\varepsilon$ you would obtain $B_{\varepsilon}(4)\setminus\{4\}\cap M_2=\emptyset$.
I leave the last one as an exercise, since it can be dealt with similar arguments.