Given $a,b,c,d,x,y,z,w \geq 0$. By the Cauchy - Schwarz inequality we have that: \begin{equation} \label{1}\tag{1} \left( ax + by + cz + dw \right) ^{2} \leq \left( a^{2} + b^{2} + c^{2} + d^{2} \right) \left( x^{2} + y^{2} + z^{2} + w^{2} \right) . \end{equation} Also, by the Cauchy - Schwarz inequality we also obtain: \begin{equation} \label{2}\tag{2} \left( ax + by + cz + dw \right) ^{2} \leq 4 a^{2} x^{2} + 4 b^{2} y^{2} + 4 c^{2} z^{2} + 4 d^{2} w^{2} . \end{equation} In general it is better to use \eqref{1} or \eqref{2} as I am looking for the tightest estimate as possible. That is, generally we have \begin{align} \label{3}\tag{3} \left( ax + by + cz + dw \right) ^{2} & \leq \left( a^{2} + b^{2} + c^{2} + d^{2} \right) \left( x^{2} + y^{2} + z^{2} + w^{2} \right) \\ & \leq 4 a^{2} x^{2} + 4 b^{2} y^{2} + 4 c^{2} z^{2} + 4 d^{2} w^{2} \end{align} or \begin{align} \label{4}\tag{4} \left( ax + by + cz + dw \right) ^{2} & \leq 4 a^{2} x^{2} + 4 b^{2} y^{2} + 4 c^{2} z^{2} + 4 d^{2} w^{2} \\ & \leq \left( a^{2} + b^{2} + c^{2} + d^{2} \right) \left( x^{2} + y^{2} + z^{2} + w^{2} \right) . \end{align}
Edit: I forgot one assumption that $d = kc$ for some $k > 0$ and also $x,y,z,w > 0$ so that there is no trivial answer. The question is when will \eqref{3} and \eqref{4} corresponding to the choice of $k$.