Is the universal cover of an integral homology sphere again an integral homology sphere? Let $\Sigma$ be an integral homology sphere (from now on I will drop the word 'integral'). 
If $\Sigma$ is simply connected, then it is homotopy equivalent to a sphere by Whitehead's Theorem, and hence homeomorphic to a sphere by the solution of the topological Poincaré conjecture. 
If $\pi_1(\Sigma)$ is infinite, then $\widetilde{\Sigma}$ is non-compact; in particular, it is not a homology sphere. 
Suppose now that $\pi_1(\Sigma)$ is finite but non-trivial. If $\dim\Sigma$ is even, then $\chi(\widetilde{\Sigma}) = |\pi_1(\Sigma)|\chi(\Sigma) = 2|\pi_1(\Sigma)|$, so $\widetilde{\Sigma}$ is not a homology sphere. If $\dim\Sigma$ is odd, then there are examples where $\widetilde{\Sigma}$ is a homology sphere, e.g. the Poincaré homology sphere which has $S^3$ as its universal cover.

If $\Sigma$ is an odd-dimensional homology sphere and $\pi_1(\Sigma)$ is finite, is $\widetilde{\Sigma}$ necessarily a homology sphere?

If the answer were yes, then $\widetilde{\Sigma}$ would be a simply connected homology sphere and hence $\widetilde{\Sigma}$ is a sphere by the argument above. In dimension three, the only homology sphere with finite fundamental group is the Poincaré homology sphere, so if there is a counterexample (which I suspect there is), it must have dimension at least five.
 A: To be concrete, take any finite simple noncyclic group with trivial Schur multiplier, e.g. $G=A_2(9)$ (see here for more examples). Then, by Kervaire's theorem, for every $k\ge 5$ there exists a $k$-dimensional integer homology sphere $M$ with $\pi_1(M)=G$. Milnor proved (see here) that if $G$ is a finite group acting freely on a sphere then every involution in $G$ has to be central. All finite noncyclic simple groups contain involutions; by simplicity, such involutions cannot be central. It follows that the universal cover of $M$ cannot be a homology sphere.   
Edit. An explicit example of an involution in $A_2(n)=PSL(3, {\mathrm F}_n)$ is given by the projectitization of the matrix
$$
\left[\begin{array}{cc}
-1&0&0\\
0&-1&0\\
0&0&1\end{array}\right]. 
$$
One can also see, by inspection, that all simple noncyclic groups of Lie type contain involutions, equivalently, have even order. It is a deep theorem of Feit and Thompson (odd order theorem) that every finite group of odd order is solvable. In other words, every non-solvable finite group contains an involution. 
