Since $A(1,4), B(7,5), C(1,8)$ lie on the circumference of the circle, the line segments $AB$, $BC$ are chords. Find the perpendicular bisectors of $AB$, $BC$. Call them $\epsilon_{AB},\epsilon_{BC}$. Determine the point of intersection of $\epsilon_{AB},\epsilon_{BC}$. This will give you the coordinates of the center. Then, compute its distance from any of the $A,B,C$. This will give you the radius.
P.S.: Of course a more straightforward method (but computationally more demanding), would be to simply substitute the coordinates of $A,B,C$ in the equation of the circle $(x-x_i)^2+(y-y_i)^2=r^2$, $i=A,B,C$ to obtain the simultaneous equations
$$
(x-1)^2+(y-4)^2=r^2 \\ \\
(x-7)^2+(y-5)^2=r^2 \\ \\
(x-1)^2+(y-8)^2=r^2 \\ \\
$$
Solve them for $(x,y,r)$ and you are done. Note that, by elementary euclidean geometry considerations, the above system of simultaneous equations has always a unique solution, provided $A,B,C$ are not collinear.