Generally, when studying factorization theory in a commutative cancellative monoid, it often proves convenenient to ignore units by working in the reduced monoid obtained by factoring out the unit group. This is the structural form of the congruences that you mention.
Many properties of domains are purely multiplicative so can be described in terms of monoid structure. Let R be a domain with fraction field K. Let R* and K* be the
multiplicative groups of units of R and K respectively. Then
G(R), the divisibility group of R, is the factor group K*/R*.
R is a UFD $\iff$ G(R) is a sum of copies of $\rm\:\mathbb Z\:.$
R is a gcd-domain $\iff$ G(R) is lattice-ordered (lub{x,y} exists)
R is a valuation domain $\iff$ G(R) is linearly ordered
R is a Riesz domain $\iff$ G(R) is a Riesz group, i.e.
an ordered group satisfying the Riesz interpolation property: if $\rm\:a,b \le c,d\:$ then $\rm\:a,b \le x \le c,d\:$ for some $\rm\:x\:.\:$ A domain $\rm\:R\:$ is called Riesz if every element is primal, i.e. $\rm\:A\:|\:BC\ \Rightarrow\ A = bc,\ b|B,\ c|C\:,\:$ for some $\rm\:b,c\in R\:.$
For more on divisibility groups see the following surveys:
J.L. Mott, Groups of divisibility: A unifying concept for
integral domains and partially ordered groups, Mathematics
and its Applications, no. 48, 1989, pp. 80-104.
J.L. Mott, The group of divisibility and its applications,
Conference on Commutative Algebra (Univ. Kansas, Lawrence, Kan.,
1972), Springer, Berlin, 1973, pp. 194-208. Lecture Notes in Math.,
Vol. 311. MR 49 #2712