Let $GL_n^+$ be the group of $n \times n$ real invertible matrices with positive determinant.
Let $g$ be the left-invariant Riemannian metric on $GL_n^+$ obtained by left translating the standard Euclidean inner product (Frobenius) on $T_IGL_n^+ \cong M_n \cong \mathbb{R}^{n^2}$. (i.e. for $X,Y \in M_n, \, \langle X,Y \rangle=\operatorname{tr}(X^TY) $).
$g$ is left-$GL_n$ invariant and right-$O_n$ invariant, where $O_n$ is the orthogonal group.
Question: Are there isometries of $(GL_n^+,g)$ which are not compositions of the above mentioned isometries? (i.e. do these symmetries generate the isometry group?).
Edit:
I think it might be useful to try to find the dimension of the group generated by left translations (matrix multiplications) and right orthogonal translations. Can we do that? I guess its dimension is less than $\dim O_n + \dim GL_n$.