André Nicolas, in his very neat answer to is the following matrix invertible? uses the fact that the matrix
$$ \begin{bmatrix} 1235 &2344 &1234 &1990\\ 2124 & 4123& 1990& 3026 \\ 1230 &1234 &9095 &1230\\ 1262 &2312& 2324 &3907 \end{bmatrix}$$
Modulo 2 is the identity, to show that its determinant is different from zero, something that also requires $$\det(A\mod x)\mod x=\det(A)\mod x$$ Where the modulo in $(A\mod x)$ is applied to the matrix elementwise. This happens because the determinant is a polynomial in the matrix entries and $$(a+bc^d)\mod x=(a\mod x + (b\mod x)(c\mod x)^d)\mod x$$
My question is then whether the successive application of such modular reductions could be a useful method to know if $\det(A)=0$. Perhaps this is so only in some particular situations, it would also be helpful if you show some of them.