For most types of quadratic Diophantine equations there exists an algorithm which makes it possible to find a solution (or solutions) over integers (good reference is here: https://www.alpertron.com.ar/METHODS.HTM).
However, those methods require at some stage finding integer divisors of some expression made of equation's coefficients (i.e. A,B,...F). When these are small, then this task is not an issue. However, for coefficients with many digits this becomes an arduous exercise.
Does anyone see a possibility of finding integer solutions of QDE without the need of factorization (i.e. finding integer divisors) along the process?