I saw this question and found the accepted answer to be very satisfying. However I thought about indefinite integrals and the differential in them (eg. $dx$). And a central part of the answer's argument is that $\dfrac{dy}{dx}$ is no longer a ratio, but a limit of a ratio. Seeing as there is no limit form of the antiderivative, I thought "what justifies the differential in the integral then". If $y = F(x)$ and $f(x) = F'(x)$ then $$\int f(x)dx = \int \dfrac{dy}{dx} \cdot dx$$ Obviously if we treat $dx$ like a fraction then they cancel out, and we end up summing $dy$, which is what we actually do when we take an antiderivative. This is a very compelling argument, but only in the context of hyperreals, where treating infinitesimals like fractions is justified. However, seeing as calculus was developed and made rigorous by people like Euler and the Bernoulli's much before hyperreals were made rigorous (by people like Abraham Robinson), what was the original justification for the differential? (I'm looking for an answer that doesn't delve into hyperreals or non-standard analysis)
Note:
Statements like "variable of integration" and "with respect to $x$" are irrelevant. Let me put that into context. When we do u-substitution, a central part is treating differentials like fractions. That is, Let $ u = y(x)$. Then $\dfrac{du}{dx} = y'$ Then we take $du = y'dx$ or $dx = \dfrac{du}{y'}$. You see where I'm getting at.
Further Note:
I know that there have been similar questions asked before, but I feel like their context wasn't exactly identical to mine, and furthermore, none of the answers were as solid or convincing as Arturo Magidin's.