Let $\pi: E \to B$ be a fibration of $E$ over $B$, let $F = \pi^{-1}(b)$ for some $b \in B$ be a representative fiber, and suppose that $B$ is contractible. Is it always the case (or are there some nice conditions guaranteeing) that $E$ is homotopic to $F$?
(For those curious, the context is John Milnor's work on the Milnor fibration: given an analytic function $f: \mathbf{C}^m \to \mathbf{C}$ with a singular point $f(0) = 0$ at the origin, the intersection of $f^{-1}(0)$ with a sufficiently small sphere $S_\epsilon^{2m-1}$ about the origin is transverse. Call this intersection $K$; the map $\pi(z) = f(z)/|f(z)|$ gives a locally trivial fibration of $S_\epsilon^{2m-1}-K$ over $S^1$. Milnor seems to rely implicitly on a result similar to the above.)