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$\ds{\int_{0}^{\infty}\bracks{\pars{{2015 \over 2015 + x} + \cdots +
{2 \over 2 + x} + {1 \over 1 + x} - x}^{2016} + 1}^{-1}\,\dd x:\ {\large ?}}$.
\begin{align}
&\int_{0}^{\infty}\bracks{\pars{{2015 \over 2015 + x} + \cdots +
{2 \over 2 + x} + {1 \over 1 + x} - x}^{2016} + 1}^{-1}\,\dd x
\\[5mm] = &\
\int_{0}^{\infty}{\dd x \over \mc{F}^{2016}\pars{x} + 1}\quad
\mbox{where}\quad\mc{F}\pars{x} \equiv \sum_{k = 1}^{2015}{k \over k + x} - x
\end{align}
\begin{align}
\mc{F}\pars{x} & \equiv
\sum_{k = 1}^{2015}{k \over k + x} - x =
2015 - x\sum_{k = 1}^{2015}{1 \over k + x} - x
\\[5mm] & =
2015 - x\sum_{k = 1}^{\infty}\pars{{1 \over k + x} - {1 \over k + 2015 + x}} - x \\[5mm] & =
2015 - x\pars{H_{x + 2015} - H_{x}} - x\qquad
\pars{~H_{z}:\ Harmonic\ Number~}
\end{align}
\begin{align}
&\bbx{\mc{F}\pars{x} =
2015 - \pars{\vphantom{\large A}H_{x + 2015} - H_{x} + 1}x}
\\[5mm]
&\mbox{Some characteristic behaviours of}\ \mc{F}\pars{x}\ \mbox{are}\
\left\{\begin{array}{l}
\ds{\mc{F}\pars{0} = 2015}
\\[2mm]
\ds{\mc{F}\pars{x} \to -\infty\quad \mbox{as}\quad x \to \infty}
\\[2mm]
\ds{\mc{F}'\pars{x} \leq 0\,,\quad \forall\ x \geq 0}
\\[2mm]
\ds{\mc{F}\pars{r} = 0\,,\quad r \approx 939.105}
\\[2mm]
\ds{\mc{F}\pars{939.105} \approx -6.28337 \times 10^{-4}}
\\[2mm]
\ds{\mc{F}'\pars{939.105} \approx -1.46404}
\end{array}\right.
\\[1cm]
&\mbox{Hereafter, I'll perform a numerical evaluation which is based in the Laplace Method}:
\\
&\int_{0}^{\infty}{\dd x \over \mc{F}^{2016}\pars{x} + 1} =
\int_{0}^{r}{\dd x \over \mc{F}^{2016}\pars{r - x} + 1} +
\int_{0}^{\infty}{\dd x \over \mc{F}^{2016}\pars{x + r} + 1}
\\[5mm] \approx &\
2\int_{0}^{\infty}
\expo{-\bracks{\mc{F}'\pars{r}}^{\large 2016}x^{\large 2016}}\,\dd x =
{2 \over \verts{\mc{F}'\pars{r}}}\int_{0}^{\infty}\expo{-x^{\large 2016}}\,\dd x
\\[5mm] = &\
{2 \over \verts{\mc{F}'\pars{r}}}\,{1 \over 2016}
\int_{0}^{\infty}x^{1/2016 - 1}\expo{-x}\,\dd x =
{1 \over 1008}\,{1 \over \verts{\mc{F}'\pars{r}}}\,\Gamma\pars{1 \over 2016}
\\[5mm] & \approx \bbx{1.36569}
\quad\mbox{with}\quad
\left.\mc{F}'\pars{r}\right\vert_{\ r\ \approx\ 939.105} \approx -1.46404
\end{align}
This value $\ds{\pars{~1.36569~}}$ is the numerical one reported by $\texttt{@achille hui}$ in another answer comment.