While Kf-Sansoo has given an elegant answer, if the problem asks for any real (and not just rational) solution, then it misses a second one which is a root of a quartic equation, hence normally is not easy to do by hand.
In general, the two solutions to,
$$x+\sqrt{(x+1)(x+2)}+\sqrt{(x+2)(x+3)}+\sqrt{(x+3)(x+1)} = n\tag1$$
for real $n>0$ are,
$$x = \frac{(n^2+4n+5)^2}{4(n+1)(n+2)(n+3)}-2\tag{2a}$$
and the appropriate root of,
$$-23 + 48 n - 22 n^2 + n^4 - 4 (30 - 33 n + 6 n^2 + n^3) x \\+
16 (-11 + 6 n) x^2 + 16 (-6 + n) x^3 - 16 x^4=0\tag{2b}$$
For $n = 4$, we have $x_1 = -311/840 \approx -0.37$. Then $x_2 \approx -5.12357$ as a root of,
$$73 - 232 x + 208 x^2 - 32 x^3 - 16 x^4 = 0$$
with both valid for the positive case of $\sqrt{z}$ as the graph from Walpha below shows,

$\color{green}{Edit:}$ When using Kf-Sansoo's method, we end up with an expression of form,
$$\prod^4 (c_1\sqrt{x+1}\pm c_2\sqrt{x+2}\pm c_3\sqrt{x+3}) = 0$$
Let $n=4$ and we get $x = -311/840$. Simpler, but the price to pay is we lose a second solution. Another method is to form an octic,
$$\prod^8 \big(y-(\pm\sqrt{z_1}\pm \sqrt{z_2}\pm \sqrt{z_3})\big)=0 \tag3$$
After it is formed, substitute into $(3)$ the ff,
$$y = n-x\\z_1=(x+1)(x+2)\\z_2=(x+2)(x+3)\\z_3=(x+3)(x+1)$$
and we get linear/quartic factors given by $(2a), (2b)$. Less simpler, but it yields a second valid solution.