OP is asking if
$$ [XY,Z]~=~0\qquad \stackrel{?}{\Rightarrow}\qquad [e^Xe^Y,e^Z]~=~0~? \tag{1}$$
In a comment above, user1551 has already pointed out obvious counterexamples if $X=0$ xor $Y=0$.
Here we will give a counterexample with invertible $2\times 2$ matrices, namely the Pauli matrices:
$$ X~=~ i\pi \sigma_x, \qquad Y~=~ \frac{i\pi}{2} \sigma_y, \qquad Z~=~ \frac{i\pi}{2} \sigma_z, \tag{2}$$
$$ e^X~=~ -{\bf 1}_{2\times 2}, \qquad e^Y~=~ i\sigma_y, \qquad e^Z~=~ i\sigma_z. \tag{3}$$
Now $XY$ is proportional to $\sigma_z$ and therefore commutes with $Z$; while $e^Xe^Y$ is proportional to $\sigma_y$, and hence anticommutes with $e^Z$ (rather than commutes).