If $R$ is a unique factorization domain and $F$ its field of fractions then any $z\in F$ can be represented as an irreducible fraction (i.e. $z=a/b$ with $a,b\in R$ so that $a$ and $b$ have no common non-unit factors in $R$).
What is an example of a domain $R$ where this fails, i.e., a domain $R$ and an element $z$ in the field of fractions of $R$ so that $z$ has no representation as an irreducible fraction (meaning $z=a/b$ with $a,b\in R$ always implies that $a$ and $b$ have a common non-unit factor in $R$)?