Let $R$ be a ring with unity, take $r\in R \setminus \{0\}$, and suppose that $(r) = R$ as ideals.
In the commutative case, this means that $r$ is invertible. Why? Because every element of $(r)$ is of the form $ar$, so we have $ar=1$ for some $a\in R$.
But in the non-commutative case, if we are looking at two-sided ideals, the elements of $(r)$ include all elements of the form $\sum_{i=1}^n a_i r b_i$ (and more, if we don't assume $R$ unital). So the statement $(r)=R$ is not so strong anymore.
Consider the example of a $2\times 2$ matrix ring over a field. A rank $1$ matrix is not invertible, but it generates the whole ring as an ideal, because we can produce all rank $1$ matrices by multiplying, and then easily write any matrix as a sum of rank $1$ matrices.
On the other hand, if we assume that there are no non-trivial left ideals, for example, then a similar theorem still holds: a left- or right-simple unital ring is a division ring. But again, this is because principal left and right ideals have a nice structure, while principal two-sided ideals don't.
There is still much to be said about simple rings, but this takes more complicated forms, like Artin-Wedderburn.