I received a very helpful answer from David Mitra concerning the following question:
Let $X$ be a set, $S$ = {$\emptyset$, X} and define $\mu(\emptyset) = 0$, $\mu(X) = 1$. Determine the outer measure $\mu^*$ induced by the set function $\mu: S \rightarrow [0, \infty)$ and the $\sigma$-algebra of measurable sets.
Solution:
$$ \mu^*(E)=\text{inf}\Bigl\{\ \textstyle\sum\limits_{k=1}^\infty \mu(E_k) : E\subset\bigcup_{k=1}^\infty E_k, E_k\in S\Bigr\}. $$
If $E_k\in S$, then either $E_k=\emptyset$ or $E_k=X$.
Let $E\subset X$ be non-empty. Take the covering $E_1=X$ and $E_n=\emptyset$ for $n>1$, we have $E\subset \bigcup_{k=1}^\infty E_k$ and $\sum\limits_{k=1}^\infty u(E_k)=1$. Then, for all coverings, $1=u^*(E)=\inf\sum\limits_{k=1}^\infty u(E_k) \leq \sum\limits_{k=1}^\infty u(E_k)$.
So $\mu^*(E)=\cases{1, & if $E\ne\emptyset$\cr 0, & if $E=\emptyset$}$ This defines the outer measure.
A set $E$ is measurable if $$\mu^*(T)= \mu^*(T\cap E)+\mu^*(T\cap E')$$ for all $T\subset X$.
In particular, if $E$ is measurable, we must have $$ 1=\mu^*(X)= \mu^*(X\cap E)+\mu^*(X\cap E'). $$
So $\mu^*(E)=\cases{1, & if $E\ne\emptyset$\cr 0, & if $E=\emptyset$}$ This defines the outer measure.
My question is: How would this change if $X = [1,2]$, so that $S$ = {$\emptyset$, $[1,2]$} of subsets of $R$ and $\mu(\emptyset) = 0$, $\mu([1,2])=1$? Wouldn't it be the same?
What if we are talking about S being all subsets of $R$, where $\mu: S \rightarrow R$ and $\mu(E)$ is the number of integers in E? This one is different, but wouldn't it end up being something like:
$\mu^*(E) = \inf\sum_{k=1}^\infty \mu(E_k) = \mu(E_1) + \mu(E_2) + ... + \mu(E_n) = 1 + 2 + ... + n + ...$ where each k is the number of integers. So, as $n \rightarrow \infty, \mu^*(E) \rightarrow \infty$.