You can do it like this.
If $a_3>0$ then $f(x)$ is increasing except for the region between its two turning points. To have none of the three zeros positive requires that $f(0)\geq 0$ i.e. $a_0 \geq 0$. We also need that $f(x)$ is increasing at $x=0$.
The turning points come between zeros of $f(x)$ so the other condition is that the zeros of the derivative $f'(x)$ are both negative (this deals with increasing at $x=0$ and the values can easily be expressed in terms of the coefficients). [if we did not have the condition that there were three distinct roots already, it would be possible for the derivative to have no real roots, and the condition on $a_0$ would then ensure that the one real root was not positive].
If $a_3<0$ apply the same criteria to $-f(x)$.
With $a_3>0$ the condition for three distinct real roots is equivalent to the local maximum (existing and) being greater than zero, and the local minimum being less than zero.